R&D Scientist


Vrouw in labo

Over deze funtie

  • Markt: Life Sciences
  • Branche: Pharmacie
  • Expertisegebied: R&D
  • Standplaats: Antwerpen

Wat is vereist?

  • Uren per week: 40
  • Opleidingsniveau: Professional Bachelor
  • Sluitingsdatum: donderdag 20 mei 2021

Over deze functie

  • Support protein production from small-scale expression testing to upscaling and protein purification and quality control analysis of produced proteins for H2L and LO activities in the different TA projects
  • Majority of time will be hands-on work in the laboratory
  • Perform protein expression in bacteria, yeast, baculovirus / insect cells and mammalian systems to support the purification of proteins for screening, crystallography and assay development.
  • Purify proteins using different types of chromatography (affinity, ion exchange, size exclusion) on Akta equipment.
  • Test innovative approaches to protein production including evaluation of new technologies
  • Perform quality control on produced proteins
  • Analyze, interpret, summarize and report experimental data. Maintain accurate records (electronic notebook).
  • Write and update protocols and reports.
  • Present results and conclusions at internal team meetings.
  • Assist or take responsibility for various tasks such as shipping logistics, database entry of externally produced reagents, maintenance of cell lines, etc.
  • Review reports for accuracy and completeness.
  • Communicate effectively with investigational staff, team members and functional manager.
  • Work under limited supervision with a high level of autonomy.
  • Positive attitude, enthusiastic and motivated.
  • Strictly adhere to local safety regulations and laboratory rules.

Over jou

  • B.S./B.A in Biology, Biochemistry or equivalent with 5-10 years of industry work experience is required. Master’s degree with 2 or more years industry experience or PhD degree is preferred
  • Experience in recombinant expression of proteins in various heterologous systems (E. coli bacteria, insect cells, mammalian cell lines, cell-free systems) is required
  • Expertise in the purification of high-quality proteins using standard techniques and equipment (affinity, ion exchange, size exclusion chromatography via FPLC, SDS-PAGE, Westerns) is required
  • Expertise in protein characterization using techniques such as analytical gel filtration, mass spectrometry, dynamic light scattering, nano DSF, SPR is preferred
  • Experience in protein construct design is preferred
  • Knowledge of protein crystallization and structure determination is a plus

Wat wij je bieden

Our network and expertise make it possible for us to advance your career. Brunel has a reputation of working with some of the best in the business. That's what we continually strive for. Over 40 years, we've created a global network of interesting clients and talented individuals working together through a vast array of services.

Start je sollicitatie hier!

Solliciteren bij Brunel gaat snel en gemakkelijk. Wij ontvangen graag het volgende van jou:

  • Recent CV of LinkedIn-profiel
  • Motivatiebrief (optioneel)
  • Certificaten (optioneel)
  • Referenties (optioneel)

Vragen over de vacature?

Jouw Talent Hunter, Elke Binst licht graag alles toe over deze vacature. Wanneer je contact opneemt, verwijs naar het volgende vacaturenummer:

Talent Hunter

Elke Binst
Brunel Belgium Mechelen

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